prikaz prve stranice dokumenta Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-α4β7 Therapy
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Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-α4β7 Therapy
Dentistry Journal, 10 (2022), 3; 32. https://doi.org/10.3390/dj10030032
Saltović, Ema; Mijandrušić-Sinčić, Brankica; Braut, Alen; Škrobonja, Ivana; Sever, Ella; Glažar, Irena; Pezelj-Ribarić, Sonja; Muhvić-Urek, Miranda

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Saltović, E., Mijandrušić Sinčić, B., Braut, A., Škrobonja, I., Sever, E., Glažar, I. ... Muhvić Urek, M. (2022). Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-α4β7 Therapy. Dentistry Journal, 10. (3). doi: 10.3390/dj10030032

Saltović, Ema, et al. "Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-α4β7 Therapy." Dentistry Journal, vol. 10, br. 3, 2022. https://doi.org/10.3390/dj10030032

Saltović, Ema, Brankica Mijandrušić Sinčić, Alen Braut, Ivana Škrobonja, Ella Sever, Irena Glažar, Sonja Pezelj Ribarić i Miranda Muhvić Urek. "Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-α4β7 Therapy." Dentistry Journal 10, br. 3 (2022). https://doi.org/10.3390/dj10030032

Saltović, E., et al. (2022) 'Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-α4β7 Therapy', Dentistry Journal, 10(3). doi: 10.3390/dj10030032

Saltović E, Mijandrušić Sinčić B, Braut A, Škrobonja I, Sever E, Glažar I, i sur.. Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-α4β7 Therapy. Dentistry Journal [Internet]. 23.02.2022. [pristupljeno 15.05.2024.];10(3). doi: 10.3390/dj10030032

E. Saltović, et al., "Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-α4β7 Therapy", Dentistry Journal, vol. 10, br. 3, Veljača 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:271:863437. [Citirano: 15.05.2024.]

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Naslov (engleski)Absence of Oral Opportunistic Infections in Patients with Inflammatory Bowel Disease Receiving Anti-TNF-α and Anti-Integrin-α4β7 Therapy
AutorEma Saltović
AutorBrankica Mijandrušić-Sinčić
AutorAlen Braut
AutorIvana Škrobonja
AutorElla Sever
AutorIrena Glažar
AutorSonja Pezelj-Ribarić
AutorMiranda Muhvić-Urek
Autorova ustanovaSveučilište u Rijeci
(Fakultet dentalne medicine)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Dentalna medicina
Oralna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Biological therapy of inflammatory bowel disease (IBD) carries an increased risk for the development of opportunistic infections due to immunomodulation. The aim of this study was to determine the prevalence and types of oral infections in IBD patients treated with biological (anti-TNF-α and anti-integrin-α4β7) and conventional medication protocols. The study included 20 IBD patients receiving anti-TNF-α therapy, 20 IBD patients receiving anti-integrin-α4β7 therapy and 20 IBD patients without immunomodulatory therapy. Participants completed questionnaires on medical information, oral lesions and symptoms. For each patient, clinical examination and a salivary flow rate test were performed, followed by a swab of the oral mucosa. The swab samples were cultured to identify Candida spp. and oral bacteria. No bacterial opportunistic infections were detected. Candidiasis was detected in four participants, with no significant difference between groups (p = 0.765). Hyposalivation was most common in the anti-TNF-α group, with a significant difference between groups (p = 0.036). There were no significant differences between groups in self-reported oral mucosal lesions and symptoms (p > 0.05), or in the distribution of oral mucosal lesions (p > 0.05). This study suggests that IBD patients receiving biological therapy are at no greater risk of developing oral opportunistic infections than IBD patients not receiving immunomodulatory therapy.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaDentistry Journal
Brojčani podacivol. 10, br. 3, 32
e-ISSN2304-6767
DOIhttps://doi.org/10.3390/dj10030032
URN:NBNurn:nbn:hr:271:863437
Datum objave publikacije2022-02-23
URL dokumentahttps://www.mdpi.com/2304-6767/10/3/32
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2023-01-19 08:17:04