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Exploring the feasibility of a mild and short 4-week combined upper limb and breathing exercise program as a possible home base program to decrease fatigue and improve quality of life in ambulatory and non-ambulatory multiple sclerosis individuals.
Neurological sciences, 40 (2019); 733-743. https://doi.org/10.1007/s10072-019-3707-0
Grubić Kezele, Tanja; Babić, Matea; Štimac, Damir

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Grubić Kezele, T., Babić, M. i Štimac, D. (2019). Exploring the feasibility of a mild and short 4-week combined upper limb and breathing exercise program as a possible home base program to decrease fatigue and improve quality of life in ambulatory and non-ambulatory multiple sclerosis individuals.. Neurological sciences, 40., 733-743. doi: 10.1007/s10072-019-3707-0

Grubić Kezele, Tanja, et al. "Exploring the feasibility of a mild and short 4-week combined upper limb and breathing exercise program as a possible home base program to decrease fatigue and improve quality of life in ambulatory and non-ambulatory multiple sclerosis individuals.." Neurological sciences, vol. 40, 2019, str. 733-743. https://doi.org/10.1007/s10072-019-3707-0

Grubić Kezele, Tanja, Matea Babić i Damir Štimac. "Exploring the feasibility of a mild and short 4-week combined upper limb and breathing exercise program as a possible home base program to decrease fatigue and improve quality of life in ambulatory and non-ambulatory multiple sclerosis individuals.." Neurological sciences 40 (2019): 733-743. https://doi.org/10.1007/s10072-019-3707-0

Grubić Kezele, T., Babić, M. i Štimac, D. (2019) 'Exploring the feasibility of a mild and short 4-week combined upper limb and breathing exercise program as a possible home base program to decrease fatigue and improve quality of life in ambulatory and non-ambulatory multiple sclerosis individuals.', Neurological sciences, 40, str. 733-743. doi: 10.1007/s10072-019-3707-0

Grubić Kezele T, Babić M, Štimac D. Exploring the feasibility of a mild and short 4-week combined upper limb and breathing exercise program as a possible home base program to decrease fatigue and improve quality of life in ambulatory and non-ambulatory multiple sclerosis individuals.. Neurological sciences [Internet]. 2019. [pristupljeno 24.02.2025.];40:733-743. doi: 10.1007/s10072-019-3707-0

T. Grubić Kezele, M. Babić i D. Štimac, "Exploring the feasibility of a mild and short 4-week combined upper limb and breathing exercise program as a possible home base program to decrease fatigue and improve quality of life in ambulatory and non-ambulatory multiple sclerosis individuals.", Neurological sciences, vol. 40, str. 733-743, 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:985382. [Citirano: 24.02.2025.]

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Naslov (engleski)Exploring the feasibility of a mild and short 4-week combined upper limb and breathing exercise program as a possible home base program to decrease fatigue and improve quality of life in ambulatory and non-ambulatory multiple sclerosis individuals.
AutorTanja Grubić Kezele
AutorMatea Babić
AutorDamir Štimac
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Neurologija
Sažetak (engleski)
PURPOSE: To evaluate the feasibility of a combined upper limb and breathing exercise for a home-based program and to explore its effect on primary fatigue and quality of life in ambulatory and non-ambulatory individuals with multiple sclerosis (MS) in a short time. METHOD: Nineteen individuals with MS were assigned into semi-controlled pre-post feasibility study based on Expanded Disability Status Scale (EDSS) status and divided into two groups: exercise (five ambulatory, five non- ambulatory ;... Više EDSS 1.0-8.0) and related control with no exercise (four ambulatory, five non- ambulatory ; EDSS 1.0-7.5). Exercise group performed combined upper limb and breathing exercise in a controlled group (2 days/week, 60 min/session) accompanied by independent home exercise (3 days/week, ≥ 20 min/session). Participants underwent measures of fatigue impact (Modified Fatigue Impact Scale (MFIS) and quality of life (RAND Medical outcomes study 36-item short-form health survey (SF-36)) before and after a 4-week period. RESULTS: The MFIS (physical, psychosocial, total) showed statistically significant group-by-time interaction in ambulatory (p = 0.033, d = 1.60 ; p = 0.039, d = 1.59 ; p = 0.033, d = 1.62) and non-ambulatory individuals (p = 0.009, d = 2.42 ; p = 0.018, d = 1.96 ; p = 0.0008, d = 3.92). Physical functioning (SF-36) showed statistically significant group-by-time interaction in ambulatory (p = 0.014, d = 2.14) but no significance in non-ambulatory (p = 0.368, d = 0.68) individuals. Despite the absent statistical significance, there were large intervention effects on MFIS cognitive scores for ambulatory (d = 1.28) and non- ambulatory (d = 1.47), and on other SF-36 scores for ambulatory (general health: d = 1.76 and pain: d = 1.02) and non-ambulatory (physical limitation: d = 1.03 and emotional well-being: d = 0.94) individuals. CONCLUSION: Our 4-week program reduced some aspects of fatigue and improved some aspects of quality of life in a small group of ambulatory and non- ambulatory individuals with MS. Good feasibility and significant positive changes from baseline warrant further exploratory work. TRIAL REGISTRATION: Name of the registry: The Impact of Exercise Training on Living Quality in Multiple Sclerosis. Registration: The study was registered at www.clinicaltrial.gov on July 14, 2017. First participant enrollment: August 28, 2017. URL: 602-01/17-01-147 ; Trial registration ID: NTC03222596. Sakrij dio sažetka
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaNeurological sciences
Brojčani podacivol. 40, str. 733-743
p-ISSN1590-1874
DOIhttps://doi.org/10.1007/s10072-019-3707-0
URN:NBNurn:nbn:hr:184:985382
Datum objave publikacije2019
URL dokumentahttp://bib.irb.hr/987018
Vrsta resursaTekst
Prava pristupaOgraničen pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-21 11:13:21
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