This paper is about the research of the incidence of tumors of the salivary glands in a retrospective analysis of a database extracted from the IBIS system and electronic systems at the Clinical Institute of Pathology from 2008 to 2018 at the University Hospital Center Rijeka. The aim of the study was to show what was the total number of respondents, and the incidence of tumors in relation to gender, age, localization, type of tumor (malignant or benign). It also determined the malignant potential of the tumor, recurrence, grade of malignancy and their locatization and lymph node involvement. Finally, the importance of immunohistochemistry diagnostic methods and treatment (surgery and radiotherapy) was also analysed. Overall, there were 96 patients, 41.7% of them were male and 58.3% female. The mean age was 58.4 years and only 3.1% of the patients were younger than 25. The age range of patients with malignant tumors is from 66 to 99 years of age. The most common location, regardless of malignancy, is the parotid gland (81.3%) with the superficial region od the parotid gland being the most frequent localization (61.5%). Benign tumors occured in 90 patients while 6 of the patients had a malignant form. The most common benign tumor was pleomorphic adenoma (67.7%). Of all the malignant tumors, the most common was mucoepidermoid carcinoma (50%). Of all benign tumors, 5.2% had malignant potential. Relapse occured in 5.2% of all tumors. Considering the malignant potential, there were 50% of low grade malignant tumors, 16.7% in the middle range, and 33.3% high grade. All malignant tumors (all six of them) gave metastasis; half of them in nearby organs and the other half in distant organs. The most common place of metastasis were the lymph nodes (66.7%). Immunohistochemistry was used to prove one myoepithelioma and to diagnose one acinocellular cancer. The treatment of all tumors was surgical excision of the tumor with the surrounding tissue, while in malignant tumors, postoperative radiotherapy was also used. This research has proved that these tumors are extremely rare. The incidence of tumors of salivary glands is slightly more common in women, more commonly the benign form (pleomorpic adenoma) and mucoepidermoid carcinoma (most common malignant form). The average age of the incidence of benign tumors was 60 years of age, and of malignant tumors 78 years of age. This paper also showed that cases of relapse are more common with pleomorphic adenomas, also having malignant potential. Three of the malignant tumors were low grade which means that they have a very good five-year survival prediction. All malignant tumors gave metastases. Two of the patients had adenoid cystic carcinoma with a great five-year survival regardless of the presence of metastases and positive lymph nodes. Four of the malignant tumors affected lymph nodes and according to the AJCC classification of tumors of the salivary glands belong to stage III and stage IV. Treatment for all salivary glands was surgery, while postoperative radiotherapy was used in five patients; same as the treatment in clinics in Western Europe and the United States.