prikaz prve stranice dokumenta Stability of Propolis Phenolics during Ultrasound-Assisted Extraction Procedures
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Stability of Propolis Phenolics during Ultrasound-Assisted Extraction Procedures
Foods, 13 (2024), 13; 2020. https://doi.org/10.3390/foods13132020
Malenica, Mladenka; Biesaga, Magdalena; Pedisić, Sandra; Martinović, Lara Saftić

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Malenica, M., Biesaga, M., Pedisić, S. i Martinović, L. S. (2024). Stability of Propolis Phenolics during Ultrasound-Assisted Extraction Procedures. Foods, 13. (13). doi: 10.3390/foods13132020

Malenica, Mladenka, et al. "Stability of Propolis Phenolics during Ultrasound-Assisted Extraction Procedures." Foods, vol. 13, br. 13, 2024. https://doi.org/10.3390/foods13132020

Malenica, Mladenka, Magdalena Biesaga, Sandra Pedisić i Lara Saftić Martinović. "Stability of Propolis Phenolics during Ultrasound-Assisted Extraction Procedures." Foods 13, br. 13 (2024). https://doi.org/10.3390/foods13132020

Malenica, M., et al. (2024) 'Stability of Propolis Phenolics during Ultrasound-Assisted Extraction Procedures', Foods, 13(13). doi: 10.3390/foods13132020

Malenica M, Biesaga M, Pedisić S, Martinović LS. Stability of Propolis Phenolics during Ultrasound-Assisted Extraction Procedures. Foods [Internet]. 26.06.2024. [pristupljeno 14.04.2025.];13(13). doi: 10.3390/foods13132020

M. Malenica, M. Biesaga, S. Pedisić i L. S. Martinović, "Stability of Propolis Phenolics during Ultrasound-Assisted Extraction Procedures", Foods, vol. 13, br. 13, Lipanj 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:673218. [Citirano: 14.04.2025.]

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Naslov (engleski)Stability of Propolis Phenolics during Ultrasound-Assisted Extraction Procedures
AutorMladenka Malenica
AutorMagdalena Biesaga
AutorSandra Pedisić
AutorLara Saftić Martinović
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku kemiju, biokemiju i kliničku kemiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Medicinska biokemija
Znanstveno / umjetničko
područje, polje i grana		BIOTEHNIČKE ZNANOSTI
Prehrambena tehnologija
Sažetak (engleski)
Propolis has gained popularity in recent years as a potential preventive and therapeutic agent due to its numerous health benefits, which include immune system boosting, blood pressure lowering, allergy treatment, and skin disease treatment. The pharmacological activity of propolis is primarily attributed to phenolics and their interactions with other compounds. Given that phenols account for most of propolis’s biological activity, various extraction methods are being developed. The resin–wax... Više composition of the propolis matrix necessitates the development of an extraction procedure capable of breaking matrix–phenol bonds while maintaining phenol stability. Therefore, the aim of this study was to assess the stability of two major groups of phenolic compounds, flavonoids and phenolic acids, in propolis methanol/water 50/50 (v/v) extracts obtained after ultrasound-assisted extraction (USE) under different extraction parameters (extraction time and pH) and heat reflux extraction (HRE). The methodology involved varying the USE parameters, including extraction time (5, 10, and 15 min) and pH (2 and 7), followed by analysis using liquid chromatography–tandem mass spectrometry (LC-MS/MS) to quantify phenolic recoveries. Results revealed that benzoic acid and chlorogenic acid derivatives demonstrated excellent stability across all ultrasound extraction procedures. The recoveries of flavonoids were highly diverse, with luteolin, quercitrin, and hesperetin being the most stable. Overall, neutral pH improved flavonoid recovery, whereas phenolic acids remained more stable at pH = 2. The most important optimization parameter was USE time, and it was discovered that 15 min of ultrasound resulted in the best recoveries for most of the phenols tested, implying that phenols bind strongly to the propolis matrix and require ultrasound to break the bond. However, the high variability in phenol extraction and recovery after spiking the propolis sample shows that no single extraction method can produce the highest yield of all phenols tested. As a result, when working with a complex matrix like propolis, the extraction techniques and procedures for each phenol need to be optimized. Sakrij dio sažetka
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaFoods
Brojčani podacivol. 13, br. 13, 2020
e-ISSN2304-8158
DOIhttps://doi.org/10.3390/foods13132020
URN:NBNurn:nbn:hr:184:673218
Datum objave publikacije2024-06-26
URL dokumentahttps://www.mdpi.com/2304-8158/13/13/2020
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-09-20 11:38:18
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