prikaz prve stranice dokumenta The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer
  Preuzmi
PDF 962.32 KB
Znanstveni rad - Izvorni znanstveni rad
The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer
Biomolecules, 14 (2024), 8; 925. https://doi.org/10.3390/biom14080925
Kršek, Antea; Batičić, Lara; Braut, Tamara; Sotošek, Vlatka

Citiranost:
,
Citirajte ovaj rad

Kršek, A., Batičić, L., Braut, T. i Sotošek, V. (2024). The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer. Biomolecules, 14. (8). doi: 10.3390/biom14080925

Kršek, Antea, et al. "The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer." Biomolecules, vol. 14, br. 8, 2024. https://doi.org/10.3390/biom14080925

Kršek, Antea, Lara Batičić, Tamara Braut i Vlatka Sotošek. "The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer." Biomolecules 14, br. 8 (2024). https://doi.org/10.3390/biom14080925

Kršek, A., et al. (2024) 'The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer', Biomolecules, 14(8). doi: 10.3390/biom14080925

Kršek A, Batičić L, Braut T, Sotošek V. The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer. Biomolecules [Internet]. 30.07.2024. [pristupljeno 26.02.2025.];14(8). doi: 10.3390/biom14080925

A. Kršek, L. Batičić, T. Braut i V. Sotošek, "The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer", Biomolecules, vol. 14, br. 8, Srpanj 2024. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:598599. [Citirano: 26.02.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:598599
Prijavite se u repozitorij kako biste mogli spremiti objekt u svoju listu.
Podaci o radu
Naslov (engleski)The Next Chapter in Cancer Diagnostics: Advances in HPV-Positive Head and Neck Cancer
AutorAntea Kršek
AutorLara Batičić
AutorTamara Braut
AutorVlatka Sotošek
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za anesteziologiju, reanimatologiju, hitnu i intenzivnu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku kemiju, biokemiju i kliničku kemiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za otorinolaringologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Otorinolaringologija
Sažetak (engleski)
Human papillomavirus (HPV)-associated head and neck squamous cell carcinoma (HNSCC), particularly oropharyngeal squamous cell carcinoma (OPSCC), is an increasingly prevalent pathology worldwide, especially in developed countries. For diagnosing HPV in HNSCC, the combination of p16 immunohistochemistry (IHC) and polymerase chain reaction (PCR) offers high sensitivity and specificity, with p16 IHC being a reliable initial screen and PCR confirming HPV presence. Advanced techniques like... Više next-generation sequencing (NGS) and RNA-based assays provide detailed insights but are primarily used in research settings. Regardless of HPV status, standard oncological treatments currently include surgery, radiation, and/or chemotherapy. This conventional approach does not account for the typically better prognosis of HPV-positive HNSCC patients, leading to increased chemo/radiation-induced secondary morbidities and reduced quality of life. Therefore, it is crucial to identify and detect HPV positivity and other molecular characteristics of HNSCC to personalize treatment strategies. This comprehensive review aims to summarize current knowledge on various HPV detection techniques and evaluate their advantages and disadvantages, with a focus on developing methodologies to identify new biomarkers in HPV-positive HNSCC. The review discusses direct and indirect HPV examination in tumor tissue, DNA- and RNA-based detection techniques, protein-based markers, liquid biopsy potentials, immune-related markers, epigenetic markers, novel biomarkers, and emerging technologies, providing an overall insight into the current state of knowledge. Sakrij dio sažetka
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaBiomolecules
Brojčani podacivol. 14, br. 8, 925
e-ISSN2218-273X
DOIhttps://doi.org/10.3390/biom14080925
URN:NBNurn:nbn:hr:184:598599
Datum objave publikacije2024-07-30
ProjektŠifra: IPS-2023-02-9650
Naziv (hrvatski): Endotelna disfunkcija, upala i oksidacijski stres u kardiokirurških bolesnika
Naziv (engleski): Endothelial dysfunction, inflammation and oxidative stress in patients undergoing cardiac surgery
Kratica: EDIOS
Voditelj: Vlatka Sotošek Tokmadžić
Pravna nadležnost: Hrvatska
Financijer: Hrvatska zaklada za znanost
Linija financiranja: Research Projects
URL dokumentahttps://www.mdpi.com/2218-273X/14/8/925
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2024-08-06 11:28:46
accessibility

closePristupačnostrefresh

Ako želite spremiti trajne postavke, kliknite Spremi, ako ne - vaše će se postavke poništiti kad zatvorite preglednik.