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Androgenic/Anabolic Steroid-Induced Toxic Hepatitis
Journal of Clinical Gastroenterology, 35 (2002), 4; 350-352. https://doi.org/10.1097/00004836-200210000-00013
Štimac, Davor; Milić, Sandra; Dintinjana, Renata Dobrila; Kovač, Dražen; Ristić, Smiljana

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Štimac, D., Milić, S., Dintinjana, R. D., Kovač, D. i Ristić, S. (2002). Androgenic/Anabolic Steroid-Induced Toxic Hepatitis. Journal of Clinical Gastroenterology, 35. (4), 350-352. doi: 10.1097/00004836-200210000-00013

Štimac, Davor, et al. "Androgenic/Anabolic Steroid-Induced Toxic Hepatitis." Journal of Clinical Gastroenterology, vol. 35, br. 4, 2002, str. 350-352. https://doi.org/10.1097/00004836-200210000-00013

Štimac, Davor, Sandra Milić, Renata Dobrila Dintinjana, Dražen Kovač i Smiljana Ristić. "Androgenic/Anabolic Steroid-Induced Toxic Hepatitis." Journal of Clinical Gastroenterology 35, br. 4 (2002): 350-352. https://doi.org/10.1097/00004836-200210000-00013

Štimac, D., et al. (2002) 'Androgenic/Anabolic Steroid-Induced Toxic Hepatitis', Journal of Clinical Gastroenterology, 35(4), str. 350-352. doi: 10.1097/00004836-200210000-00013

Štimac D, Milić S, Dintinjana RD, Kovač D, Ristić S. Androgenic/Anabolic Steroid-Induced Toxic Hepatitis. Journal of Clinical Gastroenterology [Internet]. 10.2002. [pristupljeno 18.03.2025.];35(4):350-352. doi: 10.1097/00004836-200210000-00013

D. Štimac, S. Milić, R. D. Dintinjana, D. Kovač i S. Ristić, "Androgenic/Anabolic Steroid-Induced Toxic Hepatitis", Journal of Clinical Gastroenterology, vol. 35, br. 4, str. 350-352, Listopad 2002. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:575205. [Citirano: 18.03.2025.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:575205
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Podaci o radu
Naslov (engleski)Androgenic/Anabolic Steroid-Induced Toxic Hepatitis
AutorDavor Štimac
AutorSandra Milić
AutorRenata Dobrila Dintinjana
AutorDražen Kovač
AutorSmiljana Ristić
MBZ: 142283
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za internu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku biologiju i genetiku)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za opću patologiju i patološku anatomiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Athletes and bodybuilders often misuse androgenic/anabolic steroids. When used in therapeutic doses, these drugs produce clinical jaundice in just a small number of recipients. We present a 26-year-old male bodybuilder who self-administered high doses of androgenic/anabolic steroids that induced liver damage. One month before admission to the hospital, he used testosterone enanthate (500 mg intramuscularly, twice weekly), stanozolol (40 mg/d), and methylandrostenediol (30 mg/d by mouth, for 5... Više weeks). On admission, his bilirubin level was 470 micromol/L (direct, 360 micromol/L), his aspartate aminotransferase (AST) level was 5,870 IU/L, his alanine aminotransferase (ALT) level was 10,580 IU/L, his alkaline phosphatase (ALP) level was 152 IU/L, his gamma-glutamyl-transpeptidase level was 140 IU/L, his albumin level was 27.6 g/L, and his prothrombin time was 29%. During the patient's prolonged hospitalization, multiple tests and liver biopsy were performed, showing only toxic hepatic lesions. The patient was provided with supportive medical treatment. Clinical signs and laboratory findings improved substantially 12 weeks after the patient discontinued androgenic/anabolic steroids. The reasons for presenting this case were the much higher values of AST and ALT levels than reported in other studies, although the values of bilirubin and ALP were similar to those found in the literature. To our knowledge, it is the first case of toxic hepatitis induced by androgenic/anabolic steroids with predominantly hepatocellular necrosis instead of intrahepatic cholestasis. Sakrij dio sažetka
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaJournal of Clinical Gastroenterology
Brojčani podacivol. 35, br. 4, str. 350-352
p-ISSN0192-0790
DOIhttps://doi.org/10.1097/00004836-200210000-00013
URN:NBNurn:nbn:hr:184:575205
Datum objave publikacije2002-10
URL dokumentahttp://journals.lww.com/00004836-200210000-00013
Vrsta resursaTekst
Prava pristupaInstitucijski pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-09-19 10:57:07
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