prikaz prve stranice dokumenta Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke
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Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke
Wiener klinische Wochenschrift, 128 (2016), 1/2; 20-27. urn:nbn:hr:184:356412
Bonifačić, David; Toplak, Adrian; Benjak, Indira; Sotošek Tokmadžić, Vlatka; Lekić, Andrica; Kučić, Natalia

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Bonifačić, D., Toplak, A., Benjak, I., Sotošek Tokmadžić, V., Lekić, A. i Kučić, N. (2016). Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke. Wiener klinische Wochenschrift, 128. (1/2), 20-27. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:184:356412

Bonifačić, David, et al. "Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke." Wiener klinische Wochenschrift, vol. 128, br. 1/2, 2016, str. 20-27. https://urn.nsk.hr/urn:nbn:hr:184:356412

Bonifačić, David, Adrian Toplak, Indira Benjak, Vlatka Sotošek Tokmadžić, Andrica Lekić i Natalia Kučić. "Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke." Wiener klinische Wochenschrift 128, br. 1/2 (2016): 20-27. https://urn.nsk.hr/urn:nbn:hr:184:356412

Bonifačić, D., et al. (2016) 'Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke', Wiener klinische Wochenschrift, 128(1/2), str. 20-27. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:184:356412 (Datum pristupa: 17.04.2024.)

Bonifačić D, Toplak A, Benjak I, Sotošek Tokmadžić V, Lekić A, Kučić N. Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke. Wiener klinische Wochenschrift [Internet]. 2016. [pristupljeno 17.04.2024.];128(1/2):20-27. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:356412

D. Bonifačić, A. Toplak, I. Benjak, V. Sotošek Tokmadžić, A. Lekić i N. Kučić, "Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke", Wiener klinische Wochenschrift, vol. 128, br. 1/2, str. 20-27, 2016. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:356412. [Citirano: 17.04.2024.]

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Naslov (engleski)Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke
Naslov (engleski)Monocytes and monocyte chemoattractant protein 1 (MCP-1) as early predictors of disease outcome in patients with cerebral ischemic stroke.
AutorDavid Bonifačić
AutorAdrian Toplak
AutorIndira Benjak
AutorVlatka Sotošek Tokmadžić
AutorAndrica Lekić
MBZ: 210501
AutorNatalia Kučić
MBZ: 239812
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za anesteziologiju, reanimatologiju, hitnu i intenzivnu medicinu)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za fiziologiju, imunologiju i patofiziologiju)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za medicinsku fiziku i biofiziku)
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za neurologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
In this study to identify prognostic biomarkers for ischemic stroke (IS) outcome, we monitored monocyte number and monocyte chemoattractant protein (MCP-1) concentration in peripheral blood of 44 patients with IS during the week following IS. According to the severity of IS, patients were allocated to three groups: patients with transient ischemic attack (TIA), patients with National Institute of Health Stroke Scale (NIHSS) score ≤ 12, and patients with NIHSS > 12. In patients with NIHSS > 12 statistically significant increased number of monocytes was observed on day 7. MCP-1 plasma concentration initially increased, decreased at day 3 in patients with NIHSS > 12 and increased and restored on day 7. A negative correlation between the number of monocytes and MCP-1 concentration was observed on day 3 after IS. Higher day-7 MCP-1 level was associated with higher modified Rankin Scale (mRS) value (indicating worse outcome) at 90 days post-IS in patients with NIHSS > 12. Our findings suggest that number of monocytes and plasma MCP-1 level could be clinical prognostic biomarkers as early predictors of disease outcome in patients with IS.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaWiener klinische Wochenschrift
Brojčani podacivol. 128, br. 1/2, str. 20-27
p-ISSN0043-5325
URN:NBNurn:nbn:hr:184:356412
Datum objave publikacije2016
URL dokumentahttp://bib.irb.hr/812804
Vrsta resursaTekst
Prava pristupaOgraničen pristup
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Datum i vrijeme pohrane2022-02-25 16:34:16