prikaz prve stranice dokumenta Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA)
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Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA)
Oncology Letters, 15 (2017), 1; 2335-2339. https://doi.org/10.3892/ol.2017.7576
Bačić, Ivan; Karlo, Robert; Zadro, Ana; Zadro, Zvonko; Skitarelić, Neven; Antabak, Anko

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Bačić, I., Karlo, R., Zadro, A., Zadro, Z., Skitarelić, N. i Antabak, A. (2017). Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA). Oncology Letters, 15. (1), 2335-2339. doi: 10.3892/ol.2017.7576

Bačić, Ivan, et al. "Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA)." Oncology Letters, vol. 15, br. 1, 2017, str. 2335-2339. https://doi.org/10.3892/ol.2017.7576

Bačić, Ivan, Robert Karlo, Ana Zadro, Zvonko Zadro, Neven Skitarelić i Anko Antabak. "Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA)." Oncology Letters 15, br. 1 (2017): 2335-2339. https://doi.org/10.3892/ol.2017.7576

Bačić, I., et al. (2017) 'Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA)', Oncology Letters, 15(1), str. 2335-2339. doi: 10.3892/ol.2017.7576

Bačić I, Karlo R, Zadro A, Zadro Z, Skitarelić N, Antabak A. Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA). Oncology Letters [Internet]. 2017. [pristupljeno 17.04.2024.];15(1):2335-2339. doi: 10.3892/ol.2017.7576

I. Bačić, R. Karlo, A. Zadro, Z. Zadro, N. Skitarelić i A. Antabak, "Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA)", Oncology Letters, vol. 15, br. 1, str. 2335-2339, 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:176128. [Citirano: 17.04.2024.]

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Podaci o radu
Naslov (engleski)Tumor angiogenesis as an important prognostic factor in advanced non-small cell lung cancer (Stage IIIA)
AutorIvan Bačić
MBZ: 247866
AutorRobert Karlo
MBZ: 287321
AutorAna Zadro
AutorZvonko Zadro
MBZ: 216645
AutorNeven Skitarelić
AutorAnko Antabak
MBZ: 217751
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za otorinolaringologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
The aim of the present study was to evaluate angiogenesis by determining the micro vascular density (MVD) and the expression of vascular endothelial growth factor (VEGF-A) in advanced non-small cell lung cancer (NSCLC) tumor samples, and to analyze their associations with clinical parameters and survival. Tumor tissue specimens of fifty patients (41 males and 9 females), who underwent radical surgical treatment for NSCLC in stage IIIA (T1-3N2) were collected for immunohistochemical analysis. MVD evaluation was performed using an anti-CD31 monoclonal antibody and VEGF-A expression using a polyclonal anti-VEGF-A antibody. The results were associated with two-year survival. Statistical analysis revealed significant associations in the level of angiogenesis (high MVD) and shorter survival of patients with NSCLC (P=0.0007). VEGF-A expression showed no association with micro vascular density (P=0.51) or survival (P=0.68). There was no significant association between MVD and VEGF-A. The measurable, clinical MVD parameters could be used as a reliable prognostic factor for the survival of patients with advanced NSCLC.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaOncology Letters
Brojčani podacivol. 15, br. 1, str. 2335-2339
p-ISSN1792-1074
DOIhttps://doi.org/10.3892/ol.2017.7576
URN:NBNurn:nbn:hr:184:176128
Datum objave publikacije2017
URL dokumentahttp://bib.irb.hr/956926
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2022-03-14 11:22:13