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Escape of Mutant Double-Stranded DNA Virus from Innate Immune Control
Immunity, 20 (2004), 6; 747-756. https://doi.org/10.1016/j.immuni.2004.05.006
French, Anthony R; Pingel, Jeanette T; Wagner, Markus; Bubić, Ivan; Yang, Liping; Kim, Sungjin; Koszinowski, Ulrich; Jonjić, Stipan; Yokoyama, Wayne M

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French, A. R., Pingel, J. T., Wagner, M., Bubić, I., Yang, L., Kim, S. ... Yokoyama, W. M. (2004). Escape of Mutant Double-Stranded DNA Virus from Innate Immune Control. Immunity, 20. (6), 747-756. doi: 10.1016/j.immuni.2004.05.006

French, Anthony R, et al. "Escape of Mutant Double-Stranded DNA Virus from Innate Immune Control." Immunity, vol. 20, br. 6, 2004, str. 747-756. https://doi.org/10.1016/j.immuni.2004.05.006

French, Anthony R, Jeanette T Pingel, Markus Wagner, Ivan Bubić, Liping Yang, Sungjin Kim, Ulrich Koszinowski, Stipan Jonjić i Wayne M Yokoyama. "Escape of Mutant Double-Stranded DNA Virus from Innate Immune Control." Immunity 20, br. 6 (2004): 747-756. https://doi.org/10.1016/j.immuni.2004.05.006

French, A. R., et al. (2004) 'Escape of Mutant Double-Stranded DNA Virus from Innate Immune Control', Immunity, 20(6), str. 747-756. doi: 10.1016/j.immuni.2004.05.006

French AR, Pingel JT, Wagner M, Bubić I, Yang L, Kim S, i sur.. Escape of Mutant Double-Stranded DNA Virus from Innate Immune Control. Immunity [Internet]. 06.2004. [pristupljeno 14.04.2024.];20(6):747-756. doi: 10.1016/j.immuni.2004.05.006

A. R. French, et al., "Escape of Mutant Double-Stranded DNA Virus from Innate Immune Control", Immunity, vol. 20, br. 6, str. 747-756, Lipanj 2004. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:150426. [Citirano: 14.04.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:150426
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Podaci o radu
Naslov (engleski)Escape of Mutant Double-Stranded DNA Virus from Innate Immune Control
AutorAnthony R French
AutorJeanette T Pingel
AutorMarkus Wagner
AutorIvan Bubić
AutorLiping Yang
AutorSungjin Kim
AutorUlrich Koszinowski
AutorStipan Jonjić
AutorWayne M Yokoyama
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za histologiju i embriologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Temeljne medicinske znanosti
Sažetak (engleski)
As innate immune system components, natural killer (NK) cells respond rapidly to infections and effectively control replication of pathogens, including murine cytomegalovirus (MCMV), a double-stranded DNA beta-herpesvirus. In the absence of NK cell control, MCMV infection results in early mortality due to uncontrolled viral replication. However, here we show that even in the face of initial NK cell control, there is late recrudescence of disease and mortality in immunodeficient mice due to the outgrowth of MCMV mutants that escape recognition by innate NK cells. These data suggest that viral infections in certain clinical settings also may be due to viral escape from innate immunity.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaImmunity
Brojčani podacivol. 20, br. 6, str. 747-756
p-ISSN1074-7613
DOIhttps://doi.org/10.1016/j.immuni.2004.05.006
URN:NBNurn:nbn:hr:184:150426
Datum objave publikacije2004-06
URL dokumentahttp://linkinghub.elsevier.com/retrieve/pii/S1074761304001384
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno-Bez prerada 4.0 međunarodna (CC BY-NC-ND 4.0)
Datum i vrijeme pohrane2018-11-22 21:22:29