prikaz prve stranice dokumenta Evolving notions on immune response in colorectal cancer and their implications for biomarker development
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Evolving notions on immune response in colorectal cancer and their implications for biomarker development
Inflammation Research, 67 (2018), 5; 375-389. https://doi.org/10.1007/s00011-017-1128-1
Grizzi, Fabio; Basso, Gianluca; Borroni, Elena Monica; Cavalleri, Tommaso; Bianchi, Paolo; Štifter, Sanja; Chiriva-Internati, Maurizio; Malesci, Alberto; Laghi, Luigi

Citirajte ovaj rad

Grizzi, F., Basso, G., Borroni, E. M., Cavalleri, T., Bianchi, P., Štifter, S. ... Laghi, L. (2018). Evolving notions on immune response in colorectal cancer and their implications for biomarker development. Inflammation Research, 67. (5), 375-389. doi: 10.1007/s00011-017-1128-1

Grizzi, Fabio, et al. "Evolving notions on immune response in colorectal cancer and their implications for biomarker development." Inflammation Research, vol. 67, br. 5, 2018, str. 375-389. https://doi.org/10.1007/s00011-017-1128-1

Grizzi, Fabio, Gianluca Basso, Elena Monica Borroni, Tommaso Cavalleri, Paolo Bianchi, Sanja Štifter, Maurizio Chiriva Internati, Alberto Malesci i Luigi Laghi. "Evolving notions on immune response in colorectal cancer and their implications for biomarker development." Inflammation Research 67, br. 5 (2018): 375-389. https://doi.org/10.1007/s00011-017-1128-1

Grizzi, F., et al. (2018) 'Evolving notions on immune response in colorectal cancer and their implications for biomarker development', Inflammation Research, 67(5), str. 375-389. doi: 10.1007/s00011-017-1128-1

Grizzi F, Basso G, Borroni EM, Cavalleri T, Bianchi P, Štifter S, i sur.. Evolving notions on immune response in colorectal cancer and their implications for biomarker development. Inflammation Research [Internet]. 2018. [pristupljeno 02.05.2024.];67(5):375-389. doi: 10.1007/s00011-017-1128-1

F. Grizzi, et al., "Evolving notions on immune response in colorectal cancer and their implications for biomarker development", Inflammation Research, vol. 67, br. 5, str. 375-389, 2018. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:043788. [Citirano: 02.05.2024.]

Za citiranje koristite ovu mrežnu adresu: https://urn.nsk.hr/urn:nbn:hr:184:043788
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Podaci o radu
Naslov (engleski)Evolving notions on immune response in colorectal cancer and their implications for biomarker development
AutorFabio Grizzi
AutorGianluca Basso
AutorElena Monica Borroni
AutorTommaso Cavalleri
AutorPaolo Bianchi
AutorSanja Štifter
AutorMaurizio Chiriva-Internati
AutorAlberto Malesci
AutorLuigi Laghi
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za opću patologiju i patološku anatomiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Patologija
Sažetak (engleski)
Colorectal cancer (CRC) still represents the third most commonly diagnosed type of cancer in men and women worldwide. CRC is acknowledged as a heterogeneous disease that develops through a multi-step sequence of events driven by clonal selections ; this observation is sustained by the fact that histologically similar tumors may have completely different outcomes, including a varied response to therapy. METHODS: In "early" and "intermediate" stage of CRC (stages II and III, respectively) there is a compelling need for new biomarkers fit to assess the metastatic potential of their disease, selecting patients with aggressive disease that might benefit from adjuvant and targeted therapies. Therefore, we review the actual notions on immune response in colorectal cancer and their implications for biomarker development. RESULTS: The recognition of the key role of immune cells in human cancer progression has recently drawn attention on the tumor immune microenvironment, as a source of new indicators of tumor outcome and response to therapy. Thus, beside consolidated histopathological biomarkers, immune endpoints are now emerging as potential biomarkers. CONCLUSIONS: The introduction of immune signatures and cellular and molecular components of the immune system as biomarkers is particularly important considering the increasing use of immune-based cancer therapies as therapeutic strategies for cancer patient
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInflammation Research
Brojčani podacivol. 67, br. 5, str. 375-389
p-ISSN1023-3830
DOIhttps://doi.org/10.1007/s00011-017-1128-1
URN:NBNurn:nbn:hr:184:043788
Datum objave publikacije2018
URL dokumentahttp://bib.irb.hr/1049760
Vrsta resursaTekst
Prava pristupaOgraničen pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-02-21 09:35:17