prikaz prve stranice dokumenta Glomerular filtration rate is an independent prognostic factor in patients with B-large cell lymphoma
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Glomerular filtration rate is an independent prognostic factor in patients with B-large cell lymphoma
Medicine, 102 (2023), 20; e33675. https://doi.org/10.1097/MD.0000000000033675
Premužić, Vedran; Bašić-Kinda, Sandra; Radman, Ivo; Dujmović, Dino; Ilić, Ivana; Živković, Neno; Maleta, Lucija; Kralik, Marko; Dobrenić, Margareta; Galunić-Bilić, Lea; Rončević, Pavle; Vodanović, Marijo; Aurer, Igor

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Premužić, V., Bašić Kinda, S., Radman, I., Dujmović, D., Ilić, I., Živković, N. ... Aurer, I. (2023). Glomerular filtration rate is an independent prognostic factor in patients with B-large cell lymphoma. Medicine, 102. (20). doi: 10.1097/MD.0000000000033675

Premužić, Vedran, et al. "Glomerular filtration rate is an independent prognostic factor in patients with B-large cell lymphoma." Medicine, vol. 102, br. 20, 2023. https://doi.org/10.1097/MD.0000000000033675

Premužić, Vedran, Sandra Bašić Kinda, Ivo Radman, Dino Dujmović, Ivana Ilić, Neno Živković, Lucija Maleta, et al. "Glomerular filtration rate is an independent prognostic factor in patients with B-large cell lymphoma." Medicine 102, br. 20 (2023). https://doi.org/10.1097/MD.0000000000033675

Premužić, V., et al. (2023) 'Glomerular filtration rate is an independent prognostic factor in patients with B-large cell lymphoma', Medicine, 102(20). doi: 10.1097/MD.0000000000033675

Premužić V, Bašić Kinda S, Radman I, Dujmović D, Ilić I, Živković N, i sur.. Glomerular filtration rate is an independent prognostic factor in patients with B-large cell lymphoma. Medicine [Internet]. 19.05.2023. [pristupljeno 05.04.2025.];102(20). doi: 10.1097/MD.0000000000033675

V. Premužić, et al., "Glomerular filtration rate is an independent prognostic factor in patients with B-large cell lymphoma", Medicine, vol. 102, br. 20, Svibanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:817362. [Citirano: 05.04.2025.]

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Naslov (engleski)Glomerular filtration rate is an independent prognostic factor in patients with B-large cell lymphoma
AutorVedran Premužić
AutorSandra Bašić-Kinda
AutorIvo Radman
AutorDino Dujmović
AutorIvana Ilić
AutorNeno Živković
AutorLucija Maleta
AutorMarko Kralik
AutorMargareta Dobrenić
AutorLea Galunić-Bilić
AutorPavle Rončević
AutorMarijo Vodanović
AutorIgor Aurer
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Chronic kidney dysfunction is associated with increased mortality in multiple cancer types. Preliminary evidence suggests the same to be true for B-large cell lymphomas (B-LCL). To analyze the relationship of glomerular filtration rate (GFR) and outcome of B-LCL in detail we collected data on outcomes of 285 consecutive patients with newly diagnosed B-LCL treated at our institution with standard rituximab-containing regimens who did not have preexisting kidney disease or urinary tract... Više obstruction at presentation. Median age was 59, range 18 to 87, 145 were male and 140 females. Forty-four had GFR < 60 mL/min, 123 had 60 to 90 mL/min, and 118 > 90 mL/min. Median follow-up of surviving patients was 49 months and estimated 3-year survival 76%. In univariate analysis age (P < .001), GFR (P = .014), stage (P < .001), performance status (P = .044), chemotherapy regimen (P < .01), and international prognostic index (IPI) (P < .001) were statistically significant prognostic factors. In multivariate analysis, age and GFR remained the only independent prognostic factors. Subtracting 1 from the IPI score of patients who had GFR > 90 mL/min and IPI > 1 resulted in a prognostic index that divides patients into 3 prognostic groups (low risk = 0-1, intermediate risk = 2-3 and high risk = 4-5) with an acceptable patient distribution frequency (38%, 39%, and 23%, respectively) and improved statistical significance and separation in comparison to IPI (5-year survival rates of 92%, 74%, and 42%, respectively). GFR is an important independent prognostic factor for B-LCL that should be taken into account in clinical decision making and data analysis and probably be incorporated in prognostic indices. Sakrij dio sažetka
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMedicine
Brojčani podacivol. 102, br. 20, e33675
p-ISSN0025-7974
DOIhttps://doi.org/10.1097/MD.0000000000033675
URN:NBNurn:nbn:hr:105:817362
Datum objave publikacije2023-05-19
URL dokumentahttps://journals.lww.com/10.1097/MD.0000000000033675
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2023-09-28 07:15:06
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