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COVID-19 pandemic and worldwide organ transplantation: a population-based study
The Lancet Public Health, 6 (2021), 10; e709-e719. https://doi.org/10.1016/S2468-2667(21)00200-0
Aubert, Olivier; Yoo, Daniel; Zielinski, Dina; Cozzi, Emanuele; Cardillo, Massimo; Dürr, Michael; Domínguez-Gil, Beatriz; Coll, Elisabeth; Da Silva, Margarida Ivo; Sallinen, Ville; Lemström, Karl; Midtvedt, Karsten; Ulloa, Camilo; Immer, Franz; Weissenbacher, Annemarie; Vallant, Natalie; Bašić-Jukić, Nikolina; Tanabe, Kazunari; Papatheodoridis, Georgios; Menoudakou, Georgia; Torres, Martin; Soratti, Carlos; Hansen Krogh, Daniela; Lefaucheur, Carmen; Ferreira, Gustavo; Silva, Helio Tedesco; Hartell, David; Forsythe, John; Mumford, Lisa; Reese, Peter P; Kerbaul, François; Jacquelinet, Christian; Vogelaar, Serge; Papalois, Vassilios; Loupy, Alexandre Više autora...

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Aubert, O., Yoo, D., Zielinski, D., Cozzi, E., Cardillo, M., Dürr, M. ... Loupy, A. (2021). COVID-19 pandemic and worldwide organ transplantation: a population-based study. The Lancet Public Health, 6. (10), e709-e719. doi: 10.1016/S2468-2667(21)00200-0

Aubert, Olivier, et al. "COVID-19 pandemic and worldwide organ transplantation: a population-based study." The Lancet Public Health, vol. 6, br. 10, 2021, str. e709-e719. https://doi.org/10.1016/S2468-2667(21)00200-0

Aubert, Olivier, Daniel Yoo, Dina Zielinski, Emanuele Cozzi, Massimo Cardillo, Michael Dürr, Beatriz Domínguez Gil, et al. "COVID-19 pandemic and worldwide organ transplantation: a population-based study." The Lancet Public Health 6, br. 10 (2021): e709-e719. https://doi.org/10.1016/S2468-2667(21)00200-0

Aubert, O., et al. (2021) 'COVID-19 pandemic and worldwide organ transplantation: a population-based study', The Lancet Public Health, 6(10), str. e709-e719. doi: 10.1016/S2468-2667(21)00200-0

Aubert O, Yoo D, Zielinski D, Cozzi E, Cardillo M, Dürr M, i sur.. COVID-19 pandemic and worldwide organ transplantation: a population-based study. The Lancet Public Health [Internet]. 10.2021. [pristupljeno 15.03.2025.];6(10):e709-e719. doi: 10.1016/S2468-2667(21)00200-0

O. Aubert, et al., "COVID-19 pandemic and worldwide organ transplantation: a population-based study", The Lancet Public Health, vol. 6, br. 10, str. e709-e719, Listopad 2021. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:496418. [Citirano: 15.03.2025.]

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Naslov (engleski)COVID-19 pandemic and worldwide organ transplantation: a population-based study
AutorOlivier Aubert
AutorDaniel Yoo
AutorDina Zielinski
AutorEmanuele Cozzi
AutorMassimo Cardillo
AutorMichael Dürr
AutorBeatriz Domínguez-Gil
AutorElisabeth Coll
AutorMargarida Ivo Da Silva
AutorVille Sallinen
AutorKarl Lemström
AutorKarsten Midtvedt
AutorCamilo Ulloa
AutorFranz Immer
AutorAnnemarie Weissenbacher
AutorNatalie Vallant
AutorNikolina Bašić-Jukić
AutorKazunari Tanabe
AutorGeorgios Papatheodoridis
AutorGeorgia Menoudakou
AutorMartin Torres
AutorCarlos Soratti
AutorDaniela Hansen Krogh
AutorCarmen Lefaucheur
AutorGustavo Ferreira
AutorHelio Tedesco Silva
AutorDavid Hartell
AutorJohn Forsythe
AutorLisa Mumford
AutorPeter P Reese
AutorFrançois Kerbaul
AutorChristian Jacquelinet
AutorSerge Vogelaar
AutorVassilios Papalois
AutorAlexandre Loupy
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: Preliminary data suggest that COVID-19 has reduced access to solid organ transplantation. However, the global consequences of the COVID-19 pandemic on transplantation rates and the effect on waitlisted patients have not been reported. We aimed to assess the effect of the COVID-19 pandemic on transplantation and investigate if the pandemic was associated with heterogeneous adaptation in terms of organ transplantation, with ensuing consequences for waitlisted patients. ----- ... Više Methods: In this population-based, observational, before-and-after study, we collected and validated nationwide cohorts of consecutive kidney, liver, lung, and heart transplants from 22 countries. Data were collected from Jan 1 to Dec 31, 2020, along with data from the same period in 2019. The analysis was done from the onset of the 100th cumulative COVID-19 case through to Dec 31, 2020. We assessed the effect of the pandemic on the worldwide organ transplantation rate and the disparity in transplant numbers within each country. We estimated the number of waitlisted patient life-years lost due to the negative effects of the pandemic. The study is registered with ClinicalTrials.gov, NCT04416256. ----- Findings: Transplant activity in all countries studied showed an overall decrease during the pandemic. Kidney transplantation was the most affected, followed by lung, liver, and heart. We identified three organ transplant rate patterns, as follows: countries with a sharp decrease in transplantation rate with a low COVID-19-related death rate; countries with a moderate decrease in transplantation rate with a moderate COVID-19-related death rate; and countries with a slight decrease in transplantation rate despite a high COVID-19-related death rate. Temporal trends revealed a marked worldwide reduction in transplant activity during the first 3 months of the pandemic, with losses stabilising after June, 2020, but decreasing again from October to December, 2020. The overall reduction in transplants during the observation time period translated to 48 239 waitlisted patient life-years lost. ----- Interpretation: We quantified the impact of the COVID-19 pandemic on worldwide organ transplantation activity and revealed heterogeneous adaptation in terms of organ transplantation, both at national levels and within countries, with detrimental consequences for waitlisted patients. Understanding how different countries and health-care systems responded to COVID-19-related challenges could facilitate improved pandemic preparedness, notably, how to safely maintain transplant programmes, both with immediate and non-immediate life-saving potential, to prevent loss of patient life-years. Sakrij dio sažetka
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeStručni rad - Stručni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaThe Lancet Public Health
Brojčani podacivol. 6, br. 10, str. e709-e719
p-ISSN2468-2667
DOIhttps://doi.org/10.1016/S2468-2667(21)00200-0
URN:NBNurn:nbn:hr:105:496418
Datum objave publikacije2021-10
URL dokumentahttps://linkinghub.elsevier.com/retrieve/pii/S2468266721002000
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2022-05-09 10:20:48
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