prikaz prve stranice dokumenta Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience
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Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience
World Journal of Transplantation, 12 (2022), 11; 378-387. https://doi.org/10.5500/wjt.v12.i11.378
Šimunov, Bojana; Mrzljak, Anna; Jurekovič, Željka; Židovec Lepej, Snježana; Bainrauch, Ana; Pavičić Šarić, Jadranka; Hruskar, Željka; Radmanić, Leona; Vilibić-Čavlek, Tatjana

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Šimunov, B., Mrzljak, A., Jurekovič, Ž., Židovec Lepej, S., Bainrauch, A., Pavičić Šarić, J. ... Vilibić Čavlek, T. (2022). Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience. World Journal of Transplantation, 12. (11), 378-387. doi: 10.5500/wjt.v12.i11.378

Šimunov, Bojana, et al. "Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience." World Journal of Transplantation, vol. 12, br. 11, 2022, str. 378-387. https://doi.org/10.5500/wjt.v12.i11.378

Šimunov, Bojana, Anna Mrzljak, Željka Jurekovič, Snježana Židovec Lepej, Ana Bainrauch, Jadranka Pavičić Šarić, Željka Hruskar, Leona Radmanić i Tatjana Vilibić Čavlek. "Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience." World Journal of Transplantation 12, br. 11 (2022): 378-387. https://doi.org/10.5500/wjt.v12.i11.378

Šimunov, B., et al. (2022) 'Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience', World Journal of Transplantation, 12(11), str. 378-387. doi: 10.5500/wjt.v12.i11.378

Šimunov B, Mrzljak A, Jurekovič Ž, Židovec Lepej S, Bainrauch A, Pavičić Šarić J, i sur.. Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience. World Journal of Transplantation [Internet]. 18.11.2022. [pristupljeno 18.03.2025.];12(11):378-387. doi: 10.5500/wjt.v12.i11.378

B. Šimunov, et al., "Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience", World Journal of Transplantation, vol. 12, br. 11, str. 378-387, Studeni 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:397186. [Citirano: 18.03.2025.]

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Podaci o radu
Naslov (engleski)Parvovirus B19 status in liver, kidney and pancreas transplant candidates: A single center experience
AutorBojana Šimunov
AutorAnna Mrzljak
AutorŽeljka Jurekovič
AutorSnježana Židovec Lepej
AutorAna Bainrauch
AutorJadranka Pavičić Šarić
AutorŽeljka Hruskar
AutorLeona Radmanić
AutorTatjana Vilibić-Čavlek
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA MEDICINSKU MIKROBIOLOGIJU I PARAZITOLOGIJU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Medicinska mikrobiologija
Sažetak (engleski)
Background: Parvovirus B19 (B19V) is associated with a wide range of clinical manifestations. The major presentation is erythema infectiosum. However, a persistent infection may cause pure red cell aplasia and chronic anemia in immunocompromized patients. The B19V seroprevalence varies with age and geographical location. Aim: To determine the B19V serological status and DNAemia in kidney, liver, and pancreas transplant candidates. Methods: Patients who underwent kidney, liver, or... Više simultaneous kidney and pancreas/liver transplantation between January 2021 and May 2022 were included in the study. The serum samples were collected before transplantation. For detection of B19V DNA, a LightMix Kit B19V EC (TIB MOLBIOL, Berlin, Germany) was used. B19V IgM and IgG antibodies were detected using a commercial ELISA test (Euroimmun, Lübeck, Germany). Results: One hundred and thirty-one transplant candidates were included in the study, 71.0% male, with an average age of 53.27 years ± 12.71 years. There were 68.7% liver, 27.5% kidney, 3.0% simul taneous pancreas/kidney transplant (SPKT), and 0.8% simultaneous liver/kidney transplant recipients. No patients had detectable B19V DNA. B19V IgG seroprevalence was 77.1%. No acute or recent infections were detected (IgM antibodies). There was no difference in the mean age of seronegative and seropositive patients (51.8 years ± 12.9 years vs 53.7 years ± 12.7 years, t = -0.603; P = 0.548). Although seropositivity was lower in patients aged less than 30 years (66.6%) compared to the patients aged 30-59 years and > 60 years (80.4% and 78.1%, respectively), this difference was not significant. In addition, there was no difference in seropositivity between male and female transplant candidates, 76.3% and 78.9% (χ 2 = 0.104; P = 0.748). The seroprevalence did not differ among organ recipients, with 77.8%, 80.6%, and 50.0% for liver, kidney, and SPKT, respectively, (χ 2 = 5.297; P = 0.151). No significant difference was found in the seroprevalence in kidney transplant patients according to dialysis modality. Seroprevalence was 71.1% in hemodialysis patients, and 100% in peritoneal dialysis patients (χ 2 = 0.799; P = 0.372). Conclusion: The B19V seroprevalence is expectedly high among kidney, liver, and pancreas transplant candidates, but there are still 22.9% of seronegative individuals who remain at risk for primary disease and severe manifestations. Further research should elucidate the necessity of B19V screening in peri-transplant management. Sakrij dio sažetka
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaWorld Journal of Transplantation
Brojčani podacivol. 12, br. 11, str. 378-387
p-ISSN2220-3230
DOIhttps://doi.org/10.5500/wjt.v12.i11.378
URN:NBNurn:nbn:hr:105:397186
Datum objave publikacije2022-11-18
URL dokumentahttps://www.wjgnet.com/2220-3230/full/v12/i11/378.htm
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Nekomercijalno 4.0 međunarodna (CC BY-NC 4.0)
Datum i vrijeme pohrane2023-06-12 09:01:00
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