prikaz prve stranice dokumenta Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta‐analysis of adjusted observational studies
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Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta‐analysis of adjusted observational studies
Clinical Cardiology, 45 (2022), 2; 198-204. https://doi.org/10.1002/clc.23776
Vrsalović, Mislav; Vrsalović Presečki, Ana; Aboyans, Victor

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Vrsalović, M., Vrsalović Presečki, A. i Aboyans, V. (2022). Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta‐analysis of adjusted observational studies. Clinical Cardiology, 45. (2), 198-204. doi: 10.1002/clc.23776

Vrsalović, Mislav, et al. "Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta‐analysis of adjusted observational studies." Clinical Cardiology, vol. 45, br. 2, 2022, str. 198-204. https://doi.org/10.1002/clc.23776

Vrsalović, Mislav, Ana Vrsalović Presečki i Victor Aboyans. "Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta‐analysis of adjusted observational studies." Clinical Cardiology 45, br. 2 (2022): 198-204. https://doi.org/10.1002/clc.23776

Vrsalović, M., Vrsalović Presečki, A. i Aboyans, V. (2022) 'Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta‐analysis of adjusted observational studies', Clinical Cardiology, 45(2), str. 198-204. doi: 10.1002/clc.23776

Vrsalović M, Vrsalović Presečki A, Aboyans V. Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta‐analysis of adjusted observational studies. Clinical Cardiology [Internet]. 02.2022. [pristupljeno 11.04.2024.];45(2):198-204. doi: 10.1002/clc.23776

M. Vrsalović, A. Vrsalović Presečki i V. Aboyans, "Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta‐analysis of adjusted observational studies", Clinical Cardiology, vol. 45, br. 2, str. 198-204, Veljača 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:186429. [Citirano: 11.04.2024.]

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Naslov (engleski)Cardiac troponins predict mortality and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta‐analysis of adjusted observational studies
AutorMislav Vrsalović
AutorAna Vrsalović Presečki
AutorVictor Aboyans
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
(KATEDRA ZA INTERNU MEDICINU)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Interna medicina
Sažetak (engleski)
Background: A significant proportion of patients (pts) with peripheral artery disease (PAD) have concomitant coronary artery disease and polyvascular involvement contributes to increased risk of death and unfavorable cardiovascular events. ----- Hypothesis: Cardiac troponins are associated with adverse cardiovascular outcomes in PAD pts. ----- Methods: We systematically searched Medline and Scopus to identify all observational cohort studies published before June 2021 (combining terms "troponin," "peripheral artery disease," "peripheral arterial disease," "intermittent claudication," and "critical limb ischemia") that evaluated the prognostic impact of troponin rise on admission on all-cause mortality and/or major cardiovascular events (MACEs; composite of myocardial infarction, stroke, and cardiovascular death) in PAD pts followed up at least 6 months. A meta-analysis was conducted using the generic inverse variance method. Heterogeneity between studies was investigated using Cochrane's Q test and I2 statistic. ----- Results: Eight studies were included in the final analysis (5313 pts) with a median follow-up of 27 months (interquartile range: 12-59 months). The prevalence of troponin positivity was 5.3% (range: 4.4%-8.7%) in pts with intermittent claudication, and 62.6% (range: 33.6%-85%) in critical limb ischemia. Elevated troponins were significantly associated with an increased risk of all-cause mortality (hazard ratio [HR]: 2.85, 95% confidence interval [CI]: 2.28-3.57; I2 = 50.97%), and MACE (HR: 2.58, 95% CI: 2.04-3.26; I2 = 4.00%) without publication bias (p = .24 and p = .10, respectively). ----- Conclusion: Troponin rise on admission is associated with adverse long-term cardiovascular outcomes in symptomatic PAD.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Pregledni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaClinical Cardiology
Brojčani podacivol. 45, br. 2, str. 198-204
p-ISSN0160-9289
e-ISSN1932-8737
DOIhttps://doi.org/10.1002/clc.23776
URN:NBNurn:nbn:hr:105:186429
Datum objave publikacije2022-02
URL dokumentahttps://onlinelibrary.wiley.com/doi/10.1002/clc.23776
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2022-10-26 07:33:10