prikaz prve stranice dokumenta Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men
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Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men
Croatian Medical Journal, 55 (2014), 1; 38-44. https://doi.org/10.3325/cmj.2014.55.38
Golubić, Karlo; Šmalcelj, Anton; Sertić, Jadranka; Juričić, Ljiljana

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Golubić, K., Šmalcelj, A., Sertić, J. i Juričić, Lj. (2014). Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men. Croatian Medical Journal, 55. (1), 38-44. doi: 10.3325/cmj.2014.55.38

Golubić, Karlo, et al. "Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men." Croatian Medical Journal, vol. 55, br. 1, 2014, str. 38-44. https://doi.org/10.3325/cmj.2014.55.38

Golubić, Karlo, Anton Šmalcelj, Jadranka Sertić i Ljiljana Juričić. "Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men." Croatian Medical Journal 55, br. 1 (2014): 38-44. https://doi.org/10.3325/cmj.2014.55.38

Golubić, K., et al. (2014) 'Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men', Croatian Medical Journal, 55(1), str. 38-44. doi: 10.3325/cmj.2014.55.38

Golubić K, Šmalcelj A, Sertić J, Juričić Lj. Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men. Croatian Medical Journal [Internet]. 02.2014. [pristupljeno 03.05.2024.];55(1):38-44. doi: 10.3325/cmj.2014.55.38

K. Golubić, A. Šmalcelj, J. Sertić i Lj. Juričić, "Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men", Croatian Medical Journal, vol. 55, br. 1, str. 38-44, Veljača 2014. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:105:167332. [Citirano: 03.05.2024.]

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Naslov (engleski)Estrogen receptor 1 gene (TA)n polymorphism is associated with lone atrial fibrillation in men
AutorKarlo Golubić
AutorAnton Šmalcelj
AutorJadranka Sertić
AutorLjiljana Juričić
Autorova ustanovaSveučilište u Zagrebu
Medicinski fakultet
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
AIM: To determine the association between the number of thymine-adenine (TA)n dinucleotide repeats in the promoter region of the gene coding for the estrogen receptor alpha (ESR1) and the prevalence of lone atrial fibrillation (AF) in men. ----- METHODS: We conducted a case-control study involving 89 men with lone AF and 166 healthy male controls. The ESR1 genotype was established by polymerase chain reaction and capillary electrophoresis. To assess the association of ESR1 genotype with AF, logistic regression models were built with AF as outcome. ----- RESULTS: Men with lone AF had significantly greater number of (TA)n repeats of single alleles than controls (mean ± standard deviation, 19.2 ± 4.2 vs 18 ± 4.3, P = 0.010). After adjustment for other factors, a unit-increase in (TA)n repeat number was associated with a significantly greater likelihood of AF (odds ratio 1.069; 95% confidence interval 1.024-1.116, P=0.002). ----- CONCLUSIONS: Our results indicate that a greater number of (TA)n repeats in the promoter region of ESR1 is associated with a significantly increased likelihood of lone atrial fibrillation in men.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian Medical Journal
Brojčani podacivol. 55, br. 1, str. 38-44
p-ISSN0353-9504
DOIhttps://doi.org/10.3325/cmj.2014.55.38
URN:NBNurn:nbn:hr:105:167332
Datum objave publikacije2014-02
URL dokumentahttps://doi.org/10.3325/cmj.2014.55.38
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
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Datum i vrijeme pohrane2024-03-27 20:09:20