prikaz prve stranice dokumenta Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?
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Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?
Case Reports in Critical Care, 2019 (2019); 2358562. https://doi.org/10.1155/2019/2358562
Tarčuković, Janja; Valenčić, Lara; Polonijo, Željka; Fućak, Ana; Dangubić, Boban; Grubješić, Igor

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Tarčuković, J., Valenčić, L., Polonijo, Ž., Fućak, A., Dangubić, B. i Grubješić, I. (2019). Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?. Case Reports in Critical Care, 2019.. doi: 10.1155/2019/2358562

Tarčuković, Janja, et al. "Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?." Case Reports in Critical Care, vol. 2019, 2019. https://doi.org/10.1155/2019/2358562

Tarčuković, Janja, Lara Valenčić, Željka Polonijo, Ana Fućak, Boban Dangubić i Igor Grubješić. "Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?." Case Reports in Critical Care 2019 (2019). https://doi.org/10.1155/2019/2358562

Tarčuković, J., et al. (2019) 'Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?', Case Reports in Critical Care, 2019. doi: 10.1155/2019/2358562

Tarčuković J, Valenčić L, Polonijo Ž, Fućak A, Dangubić B, Grubješić I. Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?. Case Reports in Critical Care [Internet]. 27.12.2019. [pristupljeno 13.04.2024.];2019. doi: 10.1155/2019/2358562

J. Tarčuković, L. Valenčić, Ž. Polonijo, A. Fućak, B. Dangubić i I. Grubješić, "Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?", Case Reports in Critical Care, vol. 2019, Prosinac 2019. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:184:295401. [Citirano: 13.04.2024.]

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Naslov (engleski)Acute Liver Failure as the Leading Manifestation of Spontaneous Tumour Lysis Syndrome in a Patient with NonHodgkin Lymphoma: Do Current Diagnostic Criteria of Tumour Lysis Syndrome Need Re-Evaluation?
AutorJanja Tarčuković
AutorLara Valenčić
AutorŽeljka Polonijo
AutorAna Fućak
AutorBoban Dangubić
AutorIgor Grubješić
Autorova ustanovaSveučilište u Rijeci
Medicinski fakultet
(Katedra za anesteziologiju, reanimatologiju, hitnu i intenzivnu medicinu)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Kliničke medicinske znanosti
Sažetak (engleski)
Tumour lysis syndrome (TLS) is a group of pathophysiological processes caused by rapid degradation of tumour cells with subsequent release of intracellular contents into the extracellular space. It is characterized by the development of systemic metabolic disturbances with or without clinical manifestations. The process usually occurs in highly proliferative, large tumours after induction of cytotoxic therapy. Rarely, however, spontaneous TLS can develop, as well as signs of multiorgan failure triggered by an excessive metabolic load and sterile inflammation. The combination of the aforementioned is thus quite unique. Here, we present a 63-year-old male in which spontaneous TLS was accompanied with acute liver failure and delineated underlying nonHodgkin lymphoma. Initial laboratory findings included hyperkalaemia, hyperphosphataemia, hypocalcaemia, uraemia, and increased creatinine levels indicating the onset of TLS with acute kidney injury. Moreover, the patient showed signs of jaundice, coagulopathy, and hepatic encephalopathy. Development of TLS with multiorgan failure prompted rapid initiation of critical care management, including vigorous intravenous fluid therapy, allopurinol treatment, high flow continuous venovenous haemodiafiltration, and commencement of chemotherapy. The case highlights the possibility of TLS as a differential diagnosis in patients presenting with multiorgan failure and the importance of early detection of this potentially challenging and fatal diagnosis.
Ključne riječi (hrvatski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Prikaz slučaja
Status objaveObjavljen
Vrsta recenzijeRecenziran
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCase Reports in Critical Care
Brojčani podacivol. 2019, 2358562
p-ISSN2090-6420
e-ISSN2090-6439
DOIhttps://doi.org/10.1155/2019/2358562
URN:NBNurn:nbn:hr:184:295401
Datum objave elektroničkog izdanja2019-12-27
URL dokumentahttps://www.hindawi.com/journals/cricc/2019/2358562/
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje 4.0 međunarodna (CC BY 4.0)
Datum i vrijeme pohrane2020-03-10 13:02:14