prikaz prve stranice dokumenta Changes of metallothionein, copper, zinc, and zinc-dependent enzymes induced by immobilization stress
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Changes of metallothionein, copper, zinc, and zinc-dependent enzymes induced by immobilization stress
Croatica Chemica Acta, 69 (1996), 1; 363-370. urn:nbn:hr:163:772074
Barišić, Karmela; Džanić, Emir; Lauc, Gordan; Dumić, Jerka; Žanić-Grubišić, Tihana; Flögel, Mirna

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Barišić, K., Džanić, E., Lauc, G., Dumić, J., Žanić Grubišić, T. i Flögel, M. (1996). Changes of metallothionein, copper, zinc, and zinc-dependent enzymes induced by immobilization stress. Croatica Chemica Acta, 69. (1), 363-370. Preuzeto s https://urn.nsk.hr/urn:nbn:hr:163:772074

Barišić, Karmela, et al. "Changes of metallothionein, copper, zinc, and zinc-dependent enzymes induced by immobilization stress." Croatica Chemica Acta, vol. 69, br. 1, 1996, str. 363-370. https://urn.nsk.hr/urn:nbn:hr:163:772074

Barišić, Karmela, Emir Džanić, Gordan Lauc, Jerka Dumić, Tihana Žanić Grubišić i Mirna Flögel. "Changes of metallothionein, copper, zinc, and zinc-dependent enzymes induced by immobilization stress." Croatica Chemica Acta 69, br. 1 (1996): 363-370. https://urn.nsk.hr/urn:nbn:hr:163:772074

Barišić, K., et al. (1996) 'Changes of metallothionein, copper, zinc, and zinc-dependent enzymes induced by immobilization stress', Croatica Chemica Acta, 69(1), str. 363-370. Preuzeto s: https://urn.nsk.hr/urn:nbn:hr:163:772074 (Datum pristupa: 13.04.2024.)

Barišić K, Džanić E, Lauc G, Dumić J, Žanić Grubišić T, Flögel M. Changes of metallothionein, copper, zinc, and zinc-dependent enzymes induced by immobilization stress. Croatica Chemica Acta [Internet]. 1996. [pristupljeno 13.04.2024.];69(1):363-370. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:772074

K. Barišić, E. Džanić, G. Lauc, J. Dumić, T. Žanić Grubišić i M. Flögel, "Changes of metallothionein, copper, zinc, and zinc-dependent enzymes induced by immobilization stress", Croatica Chemica Acta, vol. 69, br. 1, str. 363-370, 1996. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:163:772074. [Citirano: 13.04.2024.]

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Naslov (engleski)Changes of metallothionein, copper, zinc, and zinc-dependent enzymes induced by immobilization stress
AutorKarmela Barišić
AutorEmir Džanić
AutorGordan Lauc
AutorJerka Dumić
AutorTihana Žanić-Grubišić
AutorMirna Flögel
Autorova ustanovaSveučilište u Zagrebu
Farmaceutsko-biokemijski fakultet
(Zavod za biokemiju i molekularnu biologiju)
Znanstveno / umjetničko
područje, polje i grana		BIOMEDICINA I ZDRAVSTVO
Farmacija
Medicinska biokemija
Sažetak (engleski)
In order to study the effects of stress on copper (Cu), zinc (Zn), Zn- related enzymes, and metallothionein (MT) in liver, we used the immobilization procedure as an experimental model of stress. Acute immobilization stress caused changes of Zn, Cu, and MT concentrations in rat liver. The Zn level in total liver homogenates increased for 39% (p < 0.00011). This increase originated from the Zn concentration in nuclear fraction, suggesting a higher content of Zn-dependent enzymes and large molecular weight proteins. The stress induced increase of alkaline phosphatase (ALP), which is Zn- related metalloenzyme, closely followed the changes in the Zn concentration in liver. However, the activity of another Zn-dependent enzyme, 5'-nucleotidase (5'-NT), was lower after acute stress. The total Cu concentration was about twice higher in the stressed group in comparison with the control group, but no redistribution of Cu within hepatocytes was found. MT concentration was measured in the mitochondrial-lysosomal fraction of liver homogenates. It was found that acute immobilization stress caused about a 100% increase in the MT concentration in liver.
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatica Chemica Acta
Brojčani podacivol. 69, br. 1, str. 363-370
p-ISSN0011-1643
e-ISSN1334-417X
URN:NBNurn:nbn:hr:163:772074
Datum objave publikacije1996
URL dokumentahttps://hrcak.srce.hr/135968
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2020-04-29 14:08:20