Due to the significant role of organophosphates in important physiological processes, many methods of their synthesis have been developed. For the purpuse of this thesis, the following compounds were synthesized: 4,4'-dimethylbenzhydryl diethyl phosphate, 4-methylbenzhydryl diethyl phosphate, 4-fluorobenzhydryl diethyl phosphate and unsubstitued benzhydryl diethyl phosphate. These compounds are the result of a nucleophilic substitution in the reactions of silver diethyl phosphate and differently supstituted benzhydryl bromides/chlorides which were followed with removal of silver bromide/chloride. The first step of the synthesis was the reduction of corresponding benzhydryl ketons into alcohols (benzhydrols). Those benzhydrols were refluxed with acethyl bromide giving benzhydryl bromides, more reactive intermediates with better leaving groups. To obtain wanted products, benzhydryl diethyl phosphates, it was also necessary to prepare silver diethyl phosphate from diethyl chlorophosphate and silver (I) oxide. Synthesis of these specific compounds was chosen due to subsequently measured solvolytic rate constants in different protic and aprotic solvents. This was done conductometrically with the goal to determinate heterolitic reactivity of the diethyl phosphate leaving group.