The aim of this paper was to analyze the efficiency of selected banking systems using traditional and innovated methodology for measuring the efficiency of banks. Banking performance indicators can generally be divided into several categories according to the area they measure, so there are profitability indicators, asset quality indicators, solvency indicators, financing indicators and liquidity indicators. Traditional indicators are mostly calculated based on the accounting values available in the financial statements of banks. While the innovated indicators also consider the risk exposure, the quality of assets, the quality of capital, which makes them increasingly important when measuring the efficiency of banks. The paper deals with the banking systems of the euro area countries and selected EU member states, but not the euro area members, namely Bulgaria, Croatia and Romania. The paper also covered the banking system of the United States. Therefore, based on the analysis, it was concluded that the profitability of EU banks has deteriorated in recent years, while asset quality, solvency and liquidity have improved. The United States banking system is recording a positive trend of all observed indicators in recent years, with the exception of the first quarter of 2020, whose worse results are the result of a pandemic. Thus, the banks of the United States are more profitable than the banks of the European Union, which makes them more attractive to investors.