Money laundering is a type of global, deep-rooted criminal activity in which money is directed to actions for which it was not originally intended. The purpose of money laundering is to launder money gained from criminal activities and integrate it into regular cash flows. There are three phases of the process by which this is achieved, ie the process of money laundering: laying, breeding or lying down and integration. Europe as an extremely bank-centric society, and the Republic of Croatia, as an even more extreme example, due to a wide range of banking services is an extremely "fertile" area in the form of attempted criminal activities related to money laundering and terrorist financing. The Law on the Prevention of Money Laundering and Terrorist Financing is a good foundation in Croatia, but also at the international level, but they are also subject to constant refinements and additions. conventions and declarations to prevent money laundering and terrorist financing. Institutions and organizations for the prevention of money laundering are indispensable, at the European and world level and at the level of the Republic of Croatia, each with its own role and task, and the same goal. Their cooperation today seems inevitable and increases the chance of success of detected fraud and the development of new solutions in the future detection of potential illegal actions. In the Republic of Croatia, the most important body for the prevention of money laundering is the Office for the Prevention of Money Laundering within the Ministry of Finance, while the Tax Administration, the Croatian National Bank and finally commercial banks play a major role as primary targets for money launderers. The last chapter of this paper presents an example from practice in which the activities of preventing money laundering in Zagrebačka banka are described.