The term and definition of a letter, an epistle or another one of its synonyms can be found in multiple Croatian language dictionaries nowadays. The term originates from the Latin word epistula, which literally means epistle or letter, depending on the literary-historical context in which each of them was written. So, for example, in ancient Rome the definition of epistula referred to a letter, in verses or prose written to a private person; a friend, or even an imaginary person, while the early Christian era is known for epistles written for Christian communities by the apostles. Many years later, many qualities of the genre, just like some thematic components, were adopted by the Croatian Humanism and Renaissance authors, who thus created humanistic epistles written at the time when European countries fouth the wars against Otoman Empire. The antiturkish theme was used for the purpose of writing letters by Marko Marulić, the father of the Croatian literature, and the historiographer Stjepan Brodarić. Their letters to pope Adrian VI were startling testimonies to the war destruction that took place at that time on the ground of todayʹs Croatia, and their word addressed at the contemporary pope were a timeless call for concord, unity and hope for the salvation of the Christian faith in every kind of adversity.